Trials and Prospective Studies
ORCHID T/P supports our researchers in designing their trials and other interventional studies. Additionally, the platform will support remote follow up.
The aim of ORCHID T/P is to support our researchers in designing their trials and other interventional studies. As the database is nationally representative, our researchers are able to determine appropriate participant populations by checking feasibility of recruitment, sample size calculations taking into account the inclusion and exclusion criteria.
Current and previous studies
The National Institute for Health and Care Excellence (NICE) has identified >800 clinical interventions that should be discontinued or not used routinely in the NHS. Implementation of ‘Do-Not-Do’ recommendations could reduce inappropriate prescribing and lessen hospital admissions due to adverse events. However, the recommendations tend to be overlooked by clinicians due to competing commitments and limited time. Audit-based education (ABE) could be used to implement ‘Do-Not-Do’ recommendations to simplify the process for clinicians.
Project RSV ComNet
Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infections in children. Almost all children get it. Accurate estimates of the burden of RSV in primary care are necessary to assess the overall impact RSV has on society. This knowledge is critical for policymakers to make informed decisions regarding the introduction of new RSV interventions. Comparative RSV ComNet studies are also being conducted in the Netherlands, Italy, Spain and Belgium.
For the 2022/23 flu season, we will test new ways of identifying people with flu who come to see their GP. This includes taking nasopharyngeal swabs of those with flu-like symptoms and performing rapid tests at the practice, rather than sending the swab to a laboratory. These tests are known as “point-of-care tests”.
In brief, the IID3 study design comprises three population-based studies: two prospective studies in Primary Care, and a microbiology study involving diagnostic and reference microbiology and AMR determination. The research aims to address the question of whether the incidence of infectious intestinal disease (IID) in the community changed since the late 2000s.